The goal of the ACT project is to create a federated network of sites from the National Clinical and Translational Science Award (CTSA) Consortium to significantly increase participant accrual to the nation’s highest priority clinical trials. The project leverages the widespread implementation of the electronic health record (EHR) and the well-established extensive informatics and regulatory expertise within the CTSA Consortium. Leaders from CTSA programs across the country set the groundwork for the project and committed to participate in the creation of this national federated network. A major strength of the NCATS CTSA program is its networking of academic medical centers across the nation. This was recognized by the Institute of Medicine’s report of its objective evaluation of the CTSA program, which stated that the CTSA program should “…establish a national network that will accelerate the development of new diagnostics, therapeutics, and preventive interventions and, at the same time, drive innovation in clinical and translational research methods, processes, tools, and resources.”1
Many individual CTSAs are capable of identifying and engaging local patients for clinical trials and research studies through their EHR. The challenge for the CTSA consortium is to develop the informatics tools, regulatory infrastructure, and governance structures that are required to leverage the EHR across CTSA sites and thereby across the nation. If our goal is accomplished, we will revolutionize clinical and translational research across America and position America to become the leading “go to” site for human clinical trials by all Biotech and Pharma companies.
For more information regarding CTSA please see: https://ctsacentral.org/about-us/ctsa/. More information regarding the project’s structure, participation, and other project details can be found in the ACT Structure tab.
Reference: Institute of Medicine. The CTSA Program at NIH: Opportunities for Advancing Clinical and Translational Research. Washington, D.C.: The National Academies Press.; 2013.